Sr. Director, Pharmacological Sciences

US-CA-South San Francisco
Job ID
Research & Development


We are seeking a highly motivated and scientifically rigorous individual to join our team as a Senior Director of Pharmacological Sciences.  The successful candidate is collaborative and team-oriented scientist with proven leadership abilities. The Senior Director will lead a growing team responsible for in vivo studies and histological analyzes to support a robust pipeline of immunotherapy approaches in a science- and patient-centric company.  This role will have the opportunity for significant career development/progression as our business continues to grow and expand.


  • Provide leadership and oversight of the nonclinical Pharmacology and Histology groups
  • Provide strategic, scientific and managerial leadership across functional research areas and program teams as the Pharmacological Sciences representative
  • Design, manage, analyze, review, summarize, interpret and report results of in vivo pharmacology studies (primary and secondary pharmacology, mechanism of action, mechanism of disease, PK/PD, etc).
  • Nonclinical PK/PD modeling support
  • Initiate and manage relationships with contract research organizations and academic laboratories
  • Manage research collaborations
  • Develop, oversee, and manage department budget, liaising with the Head of Research and the Finance group
  • Provide input and tactical planning to nonclinical development strategy
  • Prepare reports, regulatory documents, INDs and BLAs. Ensures compliance with regulatory guidelines
  • Foster a collaborative, innovative and problem-solving culture


  • PhD in neurobiology, cell biology, pharmacology or related discipline
  • Minimum of 10 years of pharmaceutical/biotech industry experience in pharmacology departments
  • Previous supervisory/management experience leading more than 5 employees
  • Experience in immunohistochemistry and image analysis
  • Experience in immunotherapy and antibody development.
  • Proficiency in development and characterization of functional readouts to investigate novel mechanisms of action
  • Ability to synthesize and interpret diverse, multidisciplinary data sets
  • Demonstrated ability to identify, negotiate, and oversee outsourced services with vendors.
  • Experience with financial budget planning and tracking
  • Strong verbal and scientific writing skills, with experience preparing pharmacology sections for regulatory submissions (eg IND, NDA, BLA).


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