The Vice President of Clinical Development will report directly to the Chief Medical Officer and will be responsible for implementing and directing the clinical strategy of the development programs. The successful candidate will possess a solid understanding of US and international regulations and the drug approval process. A clear understanding of translational medicine is required, including but not limited to, basic pharmacokinetics/pharmacodynamics principles, the use of biomarkers, and data interpretation as they apply to drug development. This role will manage the design and execution of clinical studies, oversight and interpretation of clinical trial data and clinical interactions with cross-functional groups across the organization. This role will represent Prothena in external interactions with regulatory authorities, scientific and academic collaborators, patient advocacy organizations, and other external stakeholders. This role will also be the clinical lead responsible for successful completion of the phase 2b/3 studies, registration, and global launch of Prothena’s lead compound NEOD001.
Prothena is seeking an experienced and dynamic clinical development leader. The ideal candidate will have a strong medical orientation with business sense and pragmatism as well as high scientific and ethical integrity. S/he should have proven leadership skills including managing, developing and mentoring direct reports with the ability to inspire confidence, motivate and align a scientific team behind common goals. The successful candidate will have a track record and demonstrated success of advancing programs form proof-of-concept through late stage development. S/he will have an entrepreneurial bent and action orientation that fits with a growth oriented company.
S/he should demonstrate superior analytical and organizational skills with the ability to manage multiple projects effectively and simplify large amounts of complex information to draw valid conclusions. The successful candidate should have excellent communication skills with the ability to collaborate and influence colleagues across all levels of the organization.
The ideal candidate will be bright, eager, and have a strong results orientation with a demonstrated track record of success. This leader will be comfortable executing in uncertain environments and acting with a sense of urgency, however, will retain grace and resilience under pressure. Personal qualities of high integrity, strong ethics, collaborative nature and good interpersonal skills are required. Ultimately, they must demonstrate leadership to drive results that are needed to achieve company objectives in accordance with Prothena’s culture and core values – courageousness, creativity, selflessness and humor.
Education and/or Experience:
In terms of the performance and personal competencies required for the position, we would highlight the following:
Executing for Results